Cardiac Patients with Atrial Fibrillation |
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IDENTIFICATION : E-OTH-12-0073-011 |
This database includes 12-lead continuous recordings (from 73 ECGs from patients with persistent AF referred for cardioversion). The patients were followed for 4 weeks after cardioversion. Patients were offered ECG if they suffered from symptoms of arrhythmia recurrence at any time during the study. All patients underwent a final ECG evaluation at four weeks post-cardioversion.
Example of tracings (II, aVR, and V3) from patient 1098 from E-OTH-12-73-011
Study Design: Patients were considered asymptomatic if AF was diagnosed on routine ECG without any concomitant symptoms. Arrhythmia duration was defined as the time elapsed from symptom onset (or in case of asymptomatic AF, from the last documented SR) until cardioversion. All patients underwent external DC-cardioversion. Cardioversion was considered successful if AF was abolished followed by at least two sinus beats.
IMPORTANT: All patients successfully cardioverted underwent a 12-lead ECG prior to hospital discharge. The post-discharge ECG tracings are NOT INCLUDED in the database.
All patients were followed for four weeks. Cardioactive drugs were left unchanged for the duration of the study. The exclusion criteria for the study were pharmacological treatment with Class I or III anti-arrhythmic drugs, planned changes in pharmacological regime, overt congestive heart failure or ischaemic heart disease, or implanted pacemaker. All patients gave written informed consent. The study was approved by the local Ethics Committee of the enrolling organization and complied with the Declaration of Helsinki. The patients were rested supine for 10-20 min in a quiet room. The 12-lead ECGs were acquired prior to cardioversion.
Number of Leads: 12 lead standard configuration
Sampling Frequency : 1000Hz
Amplitude Resolution: 0.6 microVolt (16 bit)
File Naming Convention: Each filename is composed by "ID" which identifies the patients id and the letter "a".
Clinical Information: A limited list of clinical information available for these patients are described in the following table. The complete list of clinical information includes in addition: history of Afib, presence of coronary artery disease, presence of myocardial infarction, history of hypertension, ejection fraction, hypokalemia, etc...
| Unsuccessful Afib conversion* | Successful Afib conversion* | |
| N | 41 |
32 |
| Gender | 11 females |
11 females |
| Age (yrs) | 68+/-12 |
68+/-8 |
| AFib duration (days) | 162+/-182 |
130+/-121 |
* based on a four weeks follow-up after cardioversion.
Clinical Information:
| ID | ID = 'Study Identifier' |
| ECG | |
| Date of cardioversion | Date of atrial fibirllation cardioversion |
| Date of the second ECG | Date of the second ECG |
| Rhythm at follow-up (AF=0,SR=1) | Rhythm at follow-up (Atrial Fibrillation =0,Sinus Rhythm=1) |
| Follow-up (days) | Follow-up (days) |
| Male / Female (1/0) | Male / Female (1/0) |
| Age (yrs) | Age (yrs) |
| Co-morbidity | |
| hypertension | hypertension |
| Vavular disease | Vavular disease |
| Ischemic heart disease | Ischemic heart disease |
| Acute Myocardial infarction | Acute Myocardial infarction |
| 1.PCI 2.CABG 3.Both | 1.Percutaneous coronary intervention 2.coronary artery bypass graft surgery 3.Both |
| Date of most recent | Date of most recent |
| congestive heart failure | congestive heart failure |
| Diabetes Mellitus | Diabetes Mellitus |
| Any comorbidity | Any comorbidity |
| Lone AF | Lone AF |
| Previous AF episodes | Previous AF episodes |
| Afib onset and duration | |
| AF onset (unclear=0) | AF onset (unclear=0) |
| Last documented sinus rhythm | Last documented sinus rhythm |
| First Documented Afib | First Documented Afib |
| Detection (symptome:1, ECG:2, CHF:3) | Detection (symptome:1, ECG:2, Cardiac Heart Failure:3) |
| Afib duration (days) | Afib duration (days) |
| Medication | |
| Digitalis | Digitalis |
| Betablockers | Betablockers |
| Calcium inhibitor | Calcium inhibitor |
| sotalol | sotalol |
| Class 1c | Class Ic |
| Class III | Class III |
| ACEi/A2 | ACEi/A2 |
| Spironolactone | Spironolactone |
| No heart active drug (yes:1) | No heart active drug (yes:1) |
| Warfarin | Warfarin |
| Ultrasound cardiography | |
| Date | Date |
| Left artery diameter (mm) | Left artery diameter (mm) |
| Ejection Fraction (0=norm, 1=mild, 2=moderate, 3=severe) | Ejection Fraction (0=norm, 1=mild, 2=moderate, 3=severe) |
| Ejection fraction (%) | Ejection fraction (%) |
Related Publications:
(1) Holmqvist F, Stridh M, Waktare JE, Sornmo L, Olsson SB, Meurling CJ. Atrial fibrillatory rate and sinus rhythm maintenance in patients undergoing cardioversion of persistent atrial fibrillation. Eur Heart J 2006; 27(18):2201-2207.
(2) Holmqvist F, Stridh M, Waktare JE, Roijer A, Sornmo L, Platonov PG et al. Atrial fibrillation signal organization predicts sinus rhythm maintenance in patients undergoing cardioversion of atrial fibrillation. Europace 2006; 8(8):559-565.