LIst of Databases in the Warehouse
The list of databases in the warehouse for our members is provided below in the first Table. Click on the Study Unique Identifier (SUI) to access to a brief description of each dataset.
The second Table contains summarizes the database specifications: the number of leads per recordings, the sampling frequency of the ECG signals, the number of ECGs, the number of individuals (Ind.), and the size of the database.
Databases |
SUI* |
|---|---|
Thorough QT Study #1 (Including a unknown Compound with positive QT/QTc signal) |
|
Coronary Artery Patients |
|
Acute Myocardial Infarction Patients |
|
Sotalol data |
upcoming |
Thorough QT study #2
|
|
Holter with TdPs |
|
Individuals with history of drug-induced TdPs |
|
Cardiac patients with atrial fibrillation |
|
Congenital Long QT syndrome |
|
Chest pain Emergency Patients |
|
Healthy individuals
|
Database Specifications:
Database links |
Leads |
Sampling |
ECGs |
Ind. |
Size |
| Healthy individuals | 3 |
200 Hz |
201 |
201 |
22 GB |
| CAD patients | 3 |
200 Hz |
271 |
271 |
29 GB |
| AMI patients | 3 |
200 Hz |
160 |
93 |
18 GB |
| Thorough QT study #1 | 3 |
200 Hz |
175 |
34 |
6 GB |
12 |
180 Hz |
6 |
6 |
2 GB |
|
| Pts with history of TdPs | 12 |
1,000 Hz |
68 |
34 |
242 MB |
| AFib. patients | 12 |
1,000 Hz |
73 |
73 |
1.7 GB |
| Thorough QT study #2 | 12 |
1,000 Hz |
140 |
70 |
190 GB |
| Chest Pain Patients | 12 |
180 Hz |
1172 |
1154 | 336 GB |
| 2 or 3 |
200Hz |
480 |
307 |
14 GB |
|
TOTAL |
2,762 |
2,146 |
619 GB |
||
*SUI Database Naming Convention:
_ - _ _ _ - _ _ - _ _ _ _ - _ _ _
1 2 3 4 5
- Type of signal (1 letter):
- E : ECG
- B : blood pressure
- O : other
- Type of data signal (3 letters):
- HOL : Holter ambulatory ECGs
- TEL : telemetric ECGs
- STD : standard 12-lead resting ECGs
- OTH : other types of recording
- Number of leads included (2 digits).
- Number of recordings included in the database.
- Unique identification number (database entry order in the warehouse, 3 digits)
[12/16/2009]: The Director of the THEW interviewed by Technology Review published by the MIT: here.
[11/11/2009]: New Research Center to Focus on Cardiac Safety and Innovation in Pharmaceutical Industry Today: here.
[6/11/2009]: University of of Rochester and FDA Partner for ECG Database, Drug Discovery & Development Magazine. More info here
[5/6/2009] FDA website Existing Partnerships FDA’s Public-Private Partnership Program: THEW
[03/28/2009] Public and Private part- nership to help determine Clinical Biomarker Utility in Applied Clinical Trials online.com.>here
[7/26/2010] Members: Angel Medical System Inc. has joined the THEW initiative. Angel Medical Systems develops and markets cardiac devices that provide heart monitoring, alerting, and data collection. Their AngelMed Guardian system is an iimplantable cardiac monitoring and alerting system that is designed to warn cardiac patients of potentially life-threatening heart conditions.
[7/12/2010] The THEW quoted in a recent issue of the Journal of the American College of Cardiology. In a reply to a correspondence from Dr. Verrier and Nieminen on the role of T-wave alternans in hospital monitoring for torsades de pointes, Dr. Drew quoted the THEW as " a less expensive (than prospective clinical trials) and immediate available research strategy ... to validate ECG monitoring algorithms." JACC Vol. 56, No 3., 23010, 238-42.
[1/13/2010] Members: The Oxford University Computing Laboratory is the first new member for year 2010. At the heart of computing and related interdisciplinary activity at Oxford, this centre focuses on research in computer science, numerical analysis, computational biology, quantum computation, computational linguistics, and information systems. The Computational Biology Group also plays a key role in interdisciplinary initiatives across the University, including the EU FP7 projects euHeart and PreDiCT.
[05/27/2008]: "THEW Beyond QT working Group" releases an ECG marker submission form designed in collaboration with the FDA.
NHLBI Support[12/13/2009]:The University of Rochester and the NHLBI enabled the creation of a "Center for Quantitative Electrocardiography and Cardiac Safety" (CES). Read more...
Agreement[05/27/2008] FDA: Dr. J. Woodcock (Director, CDER-FDA) and Dr. Norman Stockbridge (Director for the Division of Cardiovascular and Renal Products, CDER-FDA) signed a Letter of Agreement officially starting the partnership between the FDA and University of Rochester for the THEW initiative. More...